Efficacy of the combination of 5 fluorouracil, adriamycin, and cisplatin (FAP protocol) in the treatment of metastatic cylindroma. Apropos of a case with review of the literature

F Farhat 1J KattanS CulineM BekraddaJ P Droz


1Département de médecine, institut Gustave-Roussy, Villejuif, France.

PMID: 7949584


We report the case of a 43 year-old woman who was submitted to a complete surgical resection of an Adenoid Cystic Carcinoma (ACC) of the submandibular salivary gland which was associated with diffuse lung metastases. Combination chemotherapy with fluoro-5-uracil, adriamycin, and cisplatin (FAP) induced an almost complete disappearance of the chest lesions. The literature about ACC and its chemotherapy is reviewed.