Synchronous invasive ductal carcinoma of the breast and clear cell renal carcinoma with rare presentation and behavior: a case report with a literature review

Mona Ali Hassan 1Najla Fakhrudiin 2Fadi Farhat 3


1Department of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon.

2Department of Pathology, Hammoud Hospital University Medical Center, Sidon, Lebanon.

3Department of Hematology and Oncology, Hammoud Hospital University Medical Center, Sidon, Lebanon.

PMID: 33209111

 PMCID: PMC7652543

 DOI: 10.3332/ecancer.2020.1120

Free PMC article


The presence of two or more primary tumours is a relatively uncommon phenomenon. Recently with the improvement of diagnostic modalities, such cases are increasingly reported in the literature. This paper presents a rare case of synchronous breast and renal tumour with unusual features including RCC metastasis to the duodenum and stomach, rapid recurrence of the tumour at the nephrectomy site, rapid renal cell carcinoma growth rate and the rare presence of syncytial-type giant cells in the renal cell tumour.

Keywords: clear cell renal cell carcinoma (RCC); invasive ductal carcinoma; synchronous tumours; syncytial-type giant cells.

Conflict of interest statement

No conflict of interest is declared by the authors.