Pancreatic small cell cancer

Elie El Rassy 1, Samer Tabchi 2, Hampig Raphael Kourie 3, Tarek Assi 2, Ralph Chebib 2, Fadi Farhat 2, Joseph Kattan 2

Affiliations

1Department of Oncology, Hotel Dieu de France University Hospital, Faculty of Medicine, Saint Joseph University, Lebanon, Lebanon. Electronic address: elie.rassy@hotmail.com.

2Department of Oncology, Hotel Dieu de France University Hospital, Faculty of Medicine, Saint Joseph University, Lebanon, Lebanon.

3Department of Oncology, Jules Bordet Institute, Free University of Brussels (ULB), 1, Héger-Bordet Street, Brussels, Belgium.

PMID: 26566245

DOI: https://doi.org/10.1016/j.clinre.2015.09.010

Abstract

Small cell carcinoma (SCC) is most commonly associated with lung cancer. Extra-pulmonary SCC can originate in virtually any organ system, with the gastrointestinal tract being the most common site of involvement. We review the clinical presentation, pathogenesis, histology, imaging modalities and optimal therapeutic management of PSCC in light of available evidence.